#2372 - Garry Nolan
Episode publishedPodcast: The Joe Rogan ExperienceThe Joe Rogan Experience
Transcript preview
Preview only
Joe Rogan podcast. Check it out. The Joe Rogan experience. Showing my day. Joe Rogan podcast by night, all day.
Garrett, very nice to meet you, sir.
Nice to meet you as well.
For doing this. I really appreciate it. Tell everybody what you do. Tell everybody what your official position is. You you're a professor at the School of Medicine at Stanford. What what do you do?
So my day job is in cancer research and cancer biology, mostly immunology and cancer. Much of what my laboratory does is not so much the biology of cancer, but developing instruments that create the data that allow us to analyze the complexities of how the immune system interfaces with tumors and how tumors basically re enable the immune system to help the cancer itself. So the problem has been we don't have the ability to collect enough data or not until recently to collect and understand what all of that means. So we've been kind of poking in the dark for decades. And so probably for the las
So explain that. The the immune system allows the tumors
So what happens is that there's sort of a there's a dance between the mutations that initiate a tumor and then sort of an evolution of how the tumor eventually learns how to trick the immune system to not recognize it. So we have all kinds of inter I mean, literally every day, every person, you'll develop five cancer like objects inside of your body. But the immune system and your body has a way of shutting it down very quickly. But with enough time and with enough variation, tumors will eventually evolve in a way that trick the immune system not only into not recognize them, but in fact, to h
So it's a normal function of natural human biology to create tumors?
It's not so much a normal function. It's a byproduct of what evolution is, that when the genes mutate when a cell divides or if you go out and, you know, stand in the in the sun too much, for instance, you get skin cancers because you're getting ionizing radiation that's changing the DNA, making a mutation, and some of those random mutations will initiate a cancer. So for instance, I have a mutation called MIDFE three one eight k. It's a mutation that I was born with. It didn't it wasn't in my family, and it causes both melanoma and kidney cancer, which I've had both. I've had a dozen melanoma
Keep exploring with a free account.
A free account preserves the short preview. Upgrade to Pro for the full transcript and episode chat.